The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2022

Filed:

May. 15, 2018
Applicant:

Promega Corporation, Madison, WI (US);

Inventors:

Andrew S. Dixon, Verona, WI (US);

Lance P. Encell, Fitchburg, WI (US);

Thomas Machleidt, Madison, WI (US);

Marie Schwinn, Madison, WI (US);

Keith Wood, Mt. Horeb, WI (US);

Monika Wood, Mt. Horeb, WI (US);

Kris Zimmerman, Madison, WI (US);

Assignee:

Promega Corporation, Madison, WI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/14 (2006.01); C07K 14/315 (2006.01); C07K 14/475 (2006.01); G01N 33/533 (2006.01); G01N 33/535 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); C07K 14/315 (2013.01); C07K 14/475 (2013.01); C12Y 308/01005 (2013.01); G01N 33/533 (2013.01); G01N 33/535 (2013.01); C07K 2319/61 (2013.01);
Abstract

Provided herein are substantially non-luminescent peptide/polypeptide tags that are inserted internally within a protein of interest or between N-terminal and C-terminal peptides/polypeptides. Interaction of the internally-inserted tag with a complement polypeptide/peptide that is also substantially non-luminescent results in the formation a bioluminescent reporter complex.


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