The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Jan. 22, 2018
Applicant:
Innate Pharma, Marseilles, FR;
Inventors:
Alessandro Moretta, Genoa, IT;
Mariella Della Chiesa, Santa Margherita Ligure, IT;
Assignee:
INNATE PHARMA, Marseilles, FR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 5/0783 (2010.01); C07K 16/28 (2006.01); G01N 33/569 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0646 (2013.01); A61K 39/00 (2013.01); C07K 16/2803 (2013.01); G01N 33/56972 (2013.01); A61K 9/127 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2319/30 (2013.01); Y02A 50/30 (2018.01);
Abstract
The present invention relates to novel compositions and methods for regulating an immune response in a subject. More particularly, the invention relates to specific antibodies that regulate the activity of NK cells and allow a potentiation of NK call cytotoxicity in mammalian subjects. The invention also relates to fragments and derivatives of such antibodies, as well as pharmaceutical compositions comprising the same and their uses, particularly in therapy, to increase NK cell activity or cytotoxicity in subjects.