The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 21, 2022

Filed:

May. 03, 2019
Applicant:

Université Laval, Québec, CA;

Inventors:

Benoit Gosselin, Lac Beauport, CA;

Younès Messaddeq, Quebec, CA;

Jacques Corbeil, Saint-Augustin de Desmaures, CA;

Eric Bharucha, St-Augustin-de-desmaures, CA;

Assignee:

UNIVERSITÉ LAVAL, Quebec, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); C12M 1/12 (2006.01); C12Q 1/02 (2006.01); G01N 27/02 (2006.01); C12M 1/32 (2006.01); C12M 1/00 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12M 41/46 (2013.01); C12M 23/12 (2013.01); C12M 25/04 (2013.01); C12M 29/04 (2013.01); C12Q 1/02 (2013.01); G01N 27/026 (2013.01); B01L 3/50853 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0829 (2013.01);
Abstract

There is described a cellular behaviour monitoring device for monitoring changes in behaviour of cells contained in a sample. The device generally has a well plate with a sample receiving well recessed therein. A filter membrane extends across the well plate and hermetically covers the sample receiving well. The filter membrane has nutrient-permeable and cell-impermeable pores extending through the filter membrane. The device has an electrode layer extending across the filter membrane. The electrode layer has a substrate and behaviour monitoring electrodes spaced-apart from one another in a region of the substrate, with the region being aligned with the sample receiving well. The electrode layer has nutrient-permeable apertures distributed across the region, with at least some of pores are aligned with at least some of the apertures to allow fluid communication therebetween, and nutrient exchange between the sample receiving well and a surrounding environment.


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