The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Aug. 19, 2016
Applicant:
Autolus Limited, London, GB;
Inventors:
Martin Pulé, London, GB;
Shaun Cordoba, London, GB;
Matteo Righi, London, GB;
James Sillibourne, London, GB;
Assignee:
AUTOLUS LIMITED, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61K 35/17 (2015.01); C07K 16/18 (2006.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3069 (2013.01); A61K 35/17 (2013.01); A61K 39/001102 (2018.08); A61K 39/001194 (2018.08); A61K 39/001195 (2018.08); C07K 16/18 (2013.01); C07K 16/3061 (2013.01); C12N 5/0636 (2013.01); A61K 38/00 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55522 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention provides a cell which comprises a first chimeric antigen receptor (CAR) and a second CAR, wherein the first and second CARs bind different epitopes on the same ligand. The cell may be used in a method for treating a disease, such as cancer.