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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11365205 B1

PDFFull Text
Date of Patent:
Jun. 21, 2022

Filed:

Mar. 20, 2019

Imidazolidin-2-one compounds as prmt5 modulators

Applicant:

Aurigene Discovery Technologies Limited, Bangalore, IN;

Inventors:

Dinesh Chikkanna, Bangalore, IN;

Sunil Kumar Panigrahi, Boudh, IN;

Srinivasa Raju Sammeta, Bangalore, IN;

Wohlfahrt Gerd, Helsinki, FI;

Myllymaki Mikko, Espoo, FI;

Assignee:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED, Karnataka, IN;

Attorneys:

Steven M. Shape

Dennemeyer & Associates, LLC

Primary Examiner:

Charanjit Aulakh

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4725 (2006.01); C07D 498/08 (2006.01); A61P 35/00 (2006.01); C07D 401/06 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); A61P 35/00 (2018.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to the derivatives of compound of formula (I) and pharmaceutically acceptable salts thereof. The present invention further provides the methods of preparation of compound of formula (I) and use thereof as PRMT5 inhibitors. The compounds are useful as medicaments in the treatment of conditions where PRMT5 inhibition is desired, such as cancer, metabolic disorders, inflammation, autoimmune disease and hemoglobinopathies.

Find Patent Forward Citations

Chikkanna, Dinesh. (2022). Imidazolidin-2-one compounds as prmt5 modulators (U.S. Patent No. 11365205). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11365205

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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