The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Feb. 27, 2018
Applicant:
Betta Pharmaceuticals Co., Ltd., Hangzhou, CN;
Inventors:
Xiaofeng Xu, Beijing, CN;
Jiabing Wang, Beijing, CN;
Lieming Ding, Hangzhou, CN;
Xiangyong Liu, Beijing, CN;
Assignee:
Betta Pharmaceuticals Co., Ltd., Hangzhou, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61P 35/00 (2018.01); C07D 519/00 (2013.01);
Abstract
An azatricyclic compound (as represented by Formula I) which acts as an inhibitor of fibroblast growth factor receptors (FGFR), as well as a pharmaceutical composition thereof, a preparation method, and a use therefor in the treatment of FGFR-mediated diseases are provided. The azatricyclic compound exerts an effect by means of participating in the regulation of a plurality of processes such as cell proliferation, apoptosis, migration, neovascularization, and the like.