The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Aug. 25, 2017
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Chad A. Mirkin, Wilmette, IL (US);
SonBinh T. Nguyen, Evanston, IL (US);
Resham J. Banga, Evanston, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 47/69 (2017.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); C12N 15/113 (2010.01); C12N 15/88 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6917 (2017.08); A61K 31/711 (2013.01); A61K 31/7105 (2013.01); C07H 21/02 (2013.01); C07H 21/04 (2013.01); C12N 15/113 (2013.01); C12N 15/88 (2013.01); C12N 2310/11 (2013.01); C12N 2310/141 (2013.01);
Abstract
Methods of preparing crosslinked spherical nucleic acids (SNAs) using thermoresponsive traceless templates, such as PEO-PPO-PEO block copolymers. The crosslinks can be added between oligonucleotides within the same SNA or oligonucleotides between multiple different SNAs.