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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11364272 B1

PDFFull Text
Date of Patent:
Jun. 21, 2022

Filed:

Aug. 28, 2019

Anticancer composition comprising tumor-specific oncolytic adenovirus and immune checkpoint inhibitor

Applicant:

Genemedicine Co., Ltd., Seoul, KR;

Inventors:

Chae Ok Yun, Seoul, KR;

Hyo Min Ahn, Incheon, KR;

Assignee:

GENEMEDICINE CO., LTD., Seoul, KR;

Attorney:

Sughrue Mion, PLLC

Primary Examiner:

Scott Long

Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61P 35/00 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/22 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 38/193 (2013.01); A61K 38/208 (2013.01); A61K 38/2221 (2013.01); A61P 35/00 (2018.01); A61K 45/06 (2013.01);
Abstract

The present invention relates to an anticancer composition comprising a tumor-specific oncolytic adenovirus and an immune checkpoint inhibitor. The recombinant adenovirus having IL-12 and shVEGF, or IL-12 and GM-CSF-RLX inserted therein, according to the present invention, exhibits an excellent anticancer effect by enhancing immune functions, and such anticancer effect has been confirmed to be notably enhanced through concomitant administration with an immune checkpoint inhibitor, and thus the present invention may be used as a key technique in the field of cancer treatment.

Find Patent Forward Citations

Yun, Chae. (2022). Anticancer composition comprising tumor-specific oncolytic adenovirus and immune checkpoint inhibitor (U.S. Patent No. 11364272). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11364272

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