The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Aug. 28, 2019
Applicant:
Genemedicine Co., Ltd., Seoul, KR;
Inventors:
Chae Ok Yun, Seoul, KR;
Hyo Min Ahn, Incheon, KR;
Assignee:
GENEMEDICINE CO., LTD., Seoul, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/761 (2015.01); A61P 35/00 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/22 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 38/193 (2013.01); A61K 38/208 (2013.01); A61K 38/2221 (2013.01); A61P 35/00 (2018.01); A61K 45/06 (2013.01);
Abstract
The present invention relates to an anticancer composition comprising a tumor-specific oncolytic adenovirus and an immune checkpoint inhibitor. The recombinant adenovirus having IL-12 and shVEGF, or IL-12 and GM-CSF-RLX inserted therein, according to the present invention, exhibits an excellent anticancer effect by enhancing immune functions, and such anticancer effect has been confirmed to be notably enhanced through concomitant administration with an immune checkpoint inhibitor, and thus the present invention may be used as a key technique in the field of cancer treatment.