The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 21, 2022
Filed:
Aug. 15, 2018
Applicant:
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Giovanni Cianchetta, Boxford, MA (US);
Tao Liu, Wellesley, MA (US);
Anil Kumar Padyana, Lexington, MA (US);
Zhihua Sui, Somerville, MA (US);
Zhenwei Cai, Shanghai, CN;
Dawei Cui, Shanghai, CN;
Jingjing Ji, Shanghai, CN;
Assignee:
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); C07D 241/36 (2006.01); C07D 513/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5025 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); C07D 241/36 (2013.01); C07D 513/14 (2013.01); A61K 45/06 (2013.01);
Abstract
Described herein are compounds that activate pyruvate kinase R, pharmaceutical compositions and methods of use thereof. These compounds are represented by Formula (I): wherein R, R, L, and Lare as defined herein.