The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Jul. 31, 2018
Applicant:
Quest Diagnostics Investments Llc, Secaucus, NJ (US);
Inventors:
Darren Weber, Rancho Santa Margarita, CA (US);
Nigel Clarke, Vista, CA (US);
Assignee:
Quest Diagnostics Investments Incoporated, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); H01J 49/42 (2006.01); G01N 30/32 (2006.01); B01D 15/16 (2006.01); B01D 15/20 (2006.01); B01D 15/42 (2006.01); G01N 30/16 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0045 (2013.01); B01D 15/163 (2013.01); B01D 15/203 (2013.01); B01D 15/424 (2013.01); G01N 30/16 (2013.01); G01N 30/32 (2013.01); G01N 33/68 (2013.01); H01J 49/4215 (2013.01); G01N 2030/324 (2013.01);
Abstract
Provided are methods for determining the apolipoprotein E (ApoE) phenotype in a sample by mass spectrometry; wherein the ApoE allele(s) present in the sample is determined from the identity of the ions detected by mass spectrometry. In another aspect, provided herein are methods for diagnosis or prognosis of Alzheimer's disease or dementia.