The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
May. 06, 2015
Applicant:
Is-diagnostics Ltd., Houten, NL;
Inventors:
Andries Edward Budding, Amsterdam, NL;
Paul Hendrik Maria Savelkoul, Amsterdam, NL;
Assignee:
IS-DIAGNOSTICS LTD, Houten, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); C12Q 2545/101 (2013.01); C12Q 2545/114 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/16 (2013.01);
Abstract
The present invention relates to a method of typing a microbiome for having a desirable or undesirable signature, comprising analyzing the composition of the population of microorganisms in the microbiome based on taxonomic variation in the DNA sequence of the microbial 16S-23S rRNA internal transcribed spacer (ITS) regions in the genomic DNA of the microorganisms, wherein the sequences of conserved DNA regions comprised in the 16S and 23S rRNA sequences flanking said ITS region in the genome of the microorganisms comprise primer binding sites for amplification of the ITS regions.