The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Mar. 09, 2016
Ventana Medical Systems, Inc., Tucson, AZ (US);
Christopher Bieniarz, Tucson, AZ (US);
Jerome W Kosmeder, Tucson, AZ (US);
Mark Lefever, Oro Valley, AZ (US);
Casey A Kernag, Tucson, AZ (US);
Julia Ashworth-Sharpe, Tucson, AZ (US);
Jennifer Wong, San Ramon, CA (US);
Ventana Medical Systems, Inc., Tucson, AZ (US);
Abstract
Antibody/signal-generating moiety conjugates are disclosed that include an antibody covalently linked to a signal-generating moiety through a heterobifunctional polyalkyleneglycol linker. The disclosed conjugates show exceptional signal-generation in immunohistochemical and in situ hybridization assays on tissue sections and cytology samples. In one embodiment, enzyme-metallographic detection of nucleic acid sequences with hapten-labeled probes can be accomplished using the disclosed conjugates as a primary antibody without amplification.