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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11359020 B1

PDFFull Text
Date of Patent:
Jun. 14, 2022

Filed:

Sep. 16, 2019

Agents that modulate immune cell activation and methods of use thereof

Applicants:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Gordon J. Freeman, Brookline, MA (US);

Arlene H. Sharpe, Brookline, MA (US);

Yanping Xiao, Brookline, MA (US);

Loise Francisco, Belmont, MA (US);

Rosemarie Dekruyff, Portola Valley, CA (US);

Dale Umetsu, Portola Valley, CA (US);

Assignees:

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

President and Fellows of Harvard College, Cambridge, MA (US);

Children's Medical Center Corporation, Boston, MA (US);

Attorney:

Foley Hoag LLP

Primary Examiner:

Sean E Aeder

Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); G01N 33/50 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 14/705 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 14/705 (2013.01); C07K 14/70532 (2013.01); C07K 16/28 (2013.01); G01N 33/5041 (2013.01); G01N 33/5047 (2013.01); G01N 33/6872 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2319/30 (2013.01); G01N 2333/4703 (2013.01); G01N 2333/70596 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01); G01N 2500/20 (2013.01);
Abstract

The present invention relates to compositions and methods for the immunomodulation mediated by the interaction of PD-L2 and RGMb.

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Freeman, Gordon. (2022). Agents that modulate immune cell activation and methods of use thereof (U.S. Patent No. 11359020). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11359020

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