The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
May. 18, 2016
Applicant:
Akamara Therapeutics, Inc., Philadelphia, PA (US);
Inventors:
Nimish Gupta, Delhi, IN;
Arindam Sarkar, Delhi, IN;
Heeralal Bassi, Delhi, IN;
Pradip Dutta, Delhi, IN;
Assignee:
Akamara Therapeutics, Inc., Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/00 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); A61K 9/51 (2006.01); A61K 31/28 (2006.01);
U.S. Cl.
CPC ...
C07F 15/0013 (2013.01); A61K 9/5115 (2013.01); A61K 9/5161 (2013.01); A61K 9/5192 (2013.01); A61K 31/28 (2013.01); A61K 47/543 (2017.08); A61K 47/6929 (2017.08);
Abstract
The present invention is in relation to the fields of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to improved methods for preparing lipid-conjugated platinum compounds with high purity and good yields. The present disclosure also relates to nanoparticles comprising lipid-conjugated platinum compounds with high drug loading efficiency for use in chemotherapy, and to methods for producing said nanoparticles.