The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Apr. 20, 2018
Applicants:
The Regents of the University of California, Oakland, CA (US);
Leidos Biomedical Research, Inc., Frederick, MD (US);
Inventors:
Frank McCormick, San Francisco, CA (US);
Adam Renslo, Oakland, CA (US);
David Turner, Frederick, MD (US);
Anna E. Maciag, Frederick, MD (US);
Marcin Dyba, Frederick, MD (US);
Elizabeth D. Vo, San Francisco, CA (US);
Joseph Saavedra, Thurmont, MD (US);
Vandana Kumari, Frederick, MD (US);
Assignees:
The Regents of the University of California, Oakland, CA (US);
Leidos Biomedical Research, Inc., Frederick, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 251/24 (2006.01); C07C 233/11 (2006.01); C07C 233/31 (2006.01); C07D 207/40 (2006.01); C07D 213/40 (2006.01); C07D 231/56 (2006.01); C07D 237/08 (2006.01); C07D 239/26 (2006.01); C07D 241/12 (2006.01); C07D 303/46 (2006.01); C07D 305/06 (2006.01); C07D 307/06 (2006.01); C07D 307/33 (2006.01); C07D 307/36 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 251/24 (2013.01); C07C 233/11 (2013.01); C07C 233/31 (2013.01); C07D 207/40 (2013.01); C07D 213/40 (2013.01); C07D 231/56 (2013.01); C07D 237/08 (2013.01); C07D 239/26 (2013.01); C07D 241/12 (2013.01); C07D 303/46 (2013.01); C07D 305/06 (2013.01); C07D 307/06 (2013.01); C07D 307/33 (2013.01); C07D 307/36 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract
Provided herein are the K-Ras inhibitors of the formulae: Also provided are compositions comprising thereof for treating cancer.