The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Nov. 22, 2017
Applicant:
Biohaven Pharmaceutical Holding Company Ltd., New Haven, CT (US);
Inventors:
Allen B. Reitz, Lansdale, PA (US);
Jeffery Claude Pelletier, Lafayette Hill, PA (US);
Assignee:
Biohaven Pharmaceutical Holding Company Ltd., New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/40 (2006.01);
U.S. Cl.
CPC ...
C07D 213/40 (2013.01);
Abstract
Pharmaceutical compositions of the invention include substituted Lanicemine prodrugs useful for the treatment of conditions associated with dysregulation of NMDA receptor activity such as depression and depressive disorders through the release of Lanicemine, Prodrugs of Lanicemine have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release Lanicemine in the plasma via either an enzymatic or general biophysical release process.