The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Jun. 07, 2018
Applicant:
The Administrators of the Tulane Educational Fund, New Orleans, LA (US);
Inventors:
Stephen E. Braun, New Orleans, LA (US);
Debasis Mondal, New Orleans, LA (US);
Bruce A Bunnell, New Orleans, LA (US);
Narae Lee, New Orleans, LA (US);
Assignee:
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, New Orleans, LA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 48/00 (2006.01); A61K 39/42 (2006.01); C07K 16/10 (2006.01); A61P 31/18 (2006.01); A61K 45/06 (2006.01); A61K 31/513 (2006.01); A61K 35/28 (2015.01); A61K 31/683 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/00 (2013.01); A61K 31/513 (2013.01); A61K 31/683 (2013.01); A61K 35/28 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01); C07K 16/1045 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); C12N 2740/16043 (2013.01);
Abstract
A composition of matter and method of treating HIV with mesenchymal stem cells (MSC) is disclosed. Specifically, MSCs are transduced with vectors incorporating an anti-viral fusion inhibitor, such as a C46-derived peptide or neutralizing antibody. The transduced MSCs are capable of expression the inhibitor and preventing HIV virus-cell fusion.