The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2022

Filed:

Jan. 11, 2017
Applicant:

Academia Sinica, Taipei, TW;

Inventors:

Han-Chung Wu, Taipei, TW;

Chen-Yun Yeh, Keelung, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/62 (2017.01); A61K 47/69 (2017.01); A61K 47/66 (2017.01); A61P 35/00 (2006.01); A61K 9/127 (2006.01); A61K 49/00 (2006.01); A61K 49/18 (2006.01); C07K 7/08 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/62 (2017.08); A61K 9/1271 (2013.01); A61K 47/64 (2017.08); A61K 47/66 (2017.08); A61K 47/665 (2017.08); A61K 47/6911 (2017.08); A61K 49/0084 (2013.01); A61K 49/1866 (2013.01); A61P 35/00 (2018.01); C07K 7/08 (2013.01);
Abstract

An isolated or a synthetic targeting peptide comprising an amino acid sequence that is at least 90% identical to SEQ ID NO: 8 is disclosed. The targeting peptide may be conjugated to a component selected from the group consisting of polymeric micelles, lipoprotein-based drug carriers, nanoparticle drug carriers, a chemotherapeutic agent, a micelle, a liposome, dendrimers, a polymer, a lipid, an oligonucleotide, a peptide, a polypeptide, a protein, a prostate cancer cell, a stem cell, and an imaging agent. Also disclosed are a kit for imaging and detecting the presence of prostate cancer cells in vivo or in vitro, and a composition for treating prostate cancer, inhibiting prostate cancer cell growth, inducing prostate cancer cell cytotoxicity, and/or increasing the survival rate in a prostate cancer patient.


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