The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2022

Filed:

Feb. 14, 2018
Applicant:

Comera Life Sciences, Inc., Woburn, MA (US);

Inventors:

David S. Soane, Palm Beach, FL (US);

Philip Wuthrich, Watertown, MA (US);

Robert P. Mahoney, Newbury, MA (US);

Mark Moody, Concord, MA (US);

Daniel G. Greene, Belmont, MA (US);

Neil L. Schauer, Milford, MA (US);

Assignee:

Comera Life Sciences, Inc., Woburn, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/22 (2006.01); A61K 47/18 (2017.01); A61K 9/00 (2006.01); A61K 47/12 (2006.01); A61K 47/60 (2017.01); A61K 47/24 (2006.01); A61K 47/20 (2006.01); C07K 16/00 (2006.01); A61K 47/42 (2017.01); A61K 38/38 (2006.01); A61K 38/47 (2006.01); C12N 9/36 (2006.01); C12N 9/96 (2006.01); A61K 38/19 (2006.01); A61K 38/17 (2006.01); A61K 47/02 (2006.01); A61K 38/18 (2006.01); C07K 16/22 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
A61K 47/22 (2013.01); A61K 9/0019 (2013.01); A61K 38/1793 (2013.01); A61K 38/1816 (2013.01); A61K 38/193 (2013.01); A61K 38/385 (2013.01); A61K 38/47 (2013.01); A61K 39/395 (2013.01); A61K 39/39591 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61K 47/24 (2013.01); A61K 47/42 (2013.01); A61K 47/60 (2017.08); C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/32 (2013.01); C12N 9/2462 (2013.01); C12N 9/96 (2013.01); C12Y 302/01017 (2013.01);
Abstract

Disclosed herein are methods for improving a parameter of a protein-related process comprising providing a viscosity-reducing excipient compound selected from the group consisting of hindered amines, anionic aromatics, functionalized amino acids, oligopeptides, short-chain organic acids, and low molecular weight aliphatic polyacids, and adding a viscosity-reducing amount of the viscosity-reducing excipient compound to a carrier solution for the protein-related process, wherein the carrier solution contains a protein of interest, and carrier solutions comprising a liquid medium in which is dissolved a protein of interest, and a viscosity-reducing excipient, wherein the viscosity of the carrier solution has a lower viscosity that that of a control solution that is substantially similar to the carrier solution except for the presence of the viscosity-reducing excipient.


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