The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Jan. 24, 2019
Applicant:
Universiteit Gent, Ghent, BE;
Inventors:
Assignee:
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12Q 1/6886 (2018.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01); G01N 33/49 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G01N 33/49 (2013.01);
Abstract
A treatment of cancer, particularly the treatment of neuroblastoma. Indeed, the discloses that a particular long non-coding RNA (lncRNA) is specifically up-regulated in neuroblastoma cells as compared to other cancer cells and that high expression of the lncRNA correlates with a lower survival probability. Inhibition of this lncRNA in neuroblastoma cells leads to a reduction in cell growth and induction of apoptosis and is a novel therapeutic strategy in the treatment of neuroblastoma.