The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Aug. 30, 2019
Applicant:
Biomadison, Inc., Del Mar, CA (US);
Inventors:
Francis Mark Dunning, Madison, WI (US);
Ward Tucker, Monona, WI (US);
Assignee:
BioMadison, Inc., Del Mar, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 14/435 (2006.01); C12N 9/52 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4893 (2013.01); C07K 14/43595 (2013.01); C07K 14/47 (2013.01); C07K 14/705 (2013.01); C12N 9/52 (2013.01); C12Q 1/37 (2013.01); C07K 2319/33 (2013.01); C07K 2319/50 (2013.01); C07K 2319/55 (2013.01); C07K 2319/60 (2013.01); C07K 2319/70 (2013.01); C12Y 304/24069 (2013.01);
Abstract
A protease directed to a non-neuronal SNARE protein is described. The protease is produced by selective mutation of aneurotoxin light chain, and is characterized utilizing a reporting construct that includes all or part of the non-neuronal SNARE protein. Such a protease has utility in the treatment of diseases associated with hypersecretion, where the hypersecretion is mediated by a non-neuronal SNARE protein.