The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Jan. 10, 2018
Applicant:
Amicus Therapeutics, Inc., Cranbury, NJ (US);
Inventor:
Russell Gotschall, Doylestown, PA (US);
Assignee:
Amicus Therapeutics, Inc., Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/40 (2006.01); A61K 38/47 (2006.01); A61K 31/445 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 31/445 (2013.01); C12N 9/2465 (2013.01); C12P 21/005 (2013.01); C12Y 302/01022 (2013.01);
Abstract
Described are compositions comprising α-galactosidase A enzymes with unique carbohydrate profiles, as well as methods for manufacturing and purifying such enzymes. Also described methods of treating, preventing, and/or ameliorating Fabry Disease by administering such enzymes to a subject in need thereof. Also described are compositions comprising migalastat in combination with such α-galactosidase A enzymes.