The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2022

Filed:

Apr. 18, 2016
Applicant:

Macau University of Science and Technology, Taipa, MO;

Inventors:

Zhi-Hong Jiang, Taipa, MO;

Jing-Rong Wang, Taipa, MO;

Jia-Ning Mi, Taipa, MO;

Junping Kou, Taipa, MO;

Yuwei Han, Taipa, MO;

Yingqiong Xu, Taipa, MO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/068 (2006.01); A61K 31/133 (2006.01); A61K 31/164 (2006.01); A61K 31/688 (2006.01); G01N 30/34 (2006.01); G01N 30/72 (2006.01); B01D 15/42 (2006.01); C12Q 1/04 (2006.01); G01N 33/92 (2006.01); G01N 30/00 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
A61K 36/068 (2013.01); A61K 31/133 (2013.01); A61K 31/164 (2013.01); A61K 31/688 (2013.01); B01D 15/426 (2013.01); C12Q 1/04 (2013.01); G01N 30/34 (2013.01); G01N 30/72 (2013.01); G01N 30/7233 (2013.01); G01N 33/92 (2013.01); A61K 2236/333 (2013.01); A61K 2236/39 (2013.01); A61K 2236/50 (2013.01); A61K 2236/53 (2013.01); G01N 2030/009 (2013.01); G01N 2030/027 (2013.01); G01N 2333/37 (2013.01); G01N 2405/08 (2013.01);
Abstract

A method of isolating at least one sphingolipid portion selected from a sphingoid base portion, a ceramide portion, a glycosphingolipid portion or a phosphosphingolipid portion from, in particular from wild-type, allows for obtaining sphingolipid portions having an increased amount of one of sphingoid bases, ceramides, glycosphingolipids or phosphosphingolipids. The sphingolipid portions isolated contained significant amounts of sphingolipids not reported so far, and possess exceptional immunosuppressive activities. A method of treating a subject suffering from an inflammatory disease like an autoimmune disease or an allergic disease includes administering sphingolipids isolated from, in particular from wild-type. A method of treating a subject suffering from an inflammatory disease includes administering certain sphingolipids to the subject. Still further in accordance with the present invention is a composition, in particular a pharmaceutical composition comprising at least one sphingolipid portion.


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