The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Jun. 30, 2017
Applicant:
Alterity Therapeutics Limited, Melbourne, AU;
Inventors:
Assignee:
Alterity Therapeutics Limited, Melbourne, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61P 39/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61P 39/04 (2018.01);
Abstract
The present invention relates to the use of substituted quinoline compounds for treating immunoglobulin light chain (LC) amyloidosis (AL), especially cardiotoxicity associated with immunoglobulin LC AL. In particular, the substituted quinoline compounds useful in the treatment of cardiac LC amyloidosis are 5,7-dihalo-8-hydroxyquinoline derivatives, especially 5,7-dichloro-8-hydroxyquinoline derivatives.