The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 2022
Filed:
Dec. 14, 2016
X4 Pharmaceuticals, Inc., Boston, MA (US);
Georgetown University, Washington, DC (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Robert D. Arbeit, West Newton, MA (US);
Paula Marie Ragan, Belmont, MA (US);
Michael B. Atkins, N.W. Washington, DC (US);
James W. Mier, Brookline, MA (US);
David McDermott, Milton, MA (US);
X4 Pharmaceuticals, Inc., Boston, MA (US);
Georgetown University, Washington, DC (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Abstract
The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.