The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 14, 2022

Filed:

Jan. 31, 2020
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Liangfang Zhang, San Diego, CA (US);

Zhiqing Pang, Shanghai, CN;

Ronnie H. Fang, San Diego, CA (US);

Che-Ming Jack Hu, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/50 (2006.01); A61P 39/02 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5176 (2013.01); A61K 9/5068 (2013.01); A61K 45/06 (2013.01); A61P 39/02 (2018.01); Y10S 514/823 (2013.01);
Abstract

The present invention relates treatments of a toxin in a subject. The toxin at least partially effects its toxicity in the subject via binding to a target cell of the subject. The present invention provides for methods, combinations and pharmaceutical compositions for decreasing or neutralizing the effect of a toxin in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, and an outer surface comprising a cellular membrane derived from a source cell. Exemplary toxins include acetylcholinesterase (AChE) inhibitors such as organophosphate poisoning.


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