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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11353460 B1

PDFFull Text
Date of Patent:
Jun. 07, 2022

Filed:

Jan. 17, 2019

L2a5 antibody or functional fragment thereof against tumour antigens

Applicants:

Universidade Nova DE Lisboa, Lisbon, PT;

Instituto Português DE Oncologia DO Porto Fg, Epe, Oporto, PT;

Helmholtz-zentrum Dresden-rossendorf—institute of Radiopharmaceutical Cancer Research, Dresden, DE;

Inventors:

Paula Alexandra Quintela Videira, Caparica, PT;

Carlos Manuel Mendes Novo, Caparica, PT;

Liliana Raquel Rodrigues Loureiro, Caparica, PT;

Mylène Adelaide do Rosário Carrascal, Caparica, PT;

José Alexandre Ribeiro de Castro Ferreira, Caparica, PT;

Maria Angelina de Sá Palma, Caparica, PT;

Lúcio Lara Santos, Caparica, PT;

Luís Carlos Oliveira Lima, Caparica, PT;

Wengang Chai, Caparica, PT;

Michael Bachmann, Caparica, PT;

Assignees:

UNIVERSIDADE NOVA DE LISBOA, Lisbon, PT;

INSTITUTO PORTUGUÊS DE ONCOLOGIA DO PORTO FG, EPE, Oporto, PT;

HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF—INSTITUTE OF RADIOPHARMACEUTICAL CANCER RESEARCH, Dresden, DE;

Attorney:

Patrick J. Halloran

Primary Examiner:

Laura B Goddard

Assistant Examiner:

Sarah A Alsomairy

Int. Cl.
CPC ...
G01N 33/574 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); A61P 35/00 (2018.01); C07K 16/3076 (2013.01); C07K 16/3092 (2013.01); C07K 2317/41 (2013.01); C07K 2317/565 (2013.01);
Abstract

This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.

Find Patent Forward Citations

Videira, Paula Alexandra Quintela. (2022). L2a5 antibody or functional fragment thereof against tumour antigens (U.S. Patent No. 11353460). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11353460

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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