The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Apr. 14, 2017
Applicant:
Creatv Microtech, Inc., Potomac, MD (US);
Inventors:
Daniel Adams, Basking Ridge, NJ (US);
Cha-Mei Tang, Potomac, MD (US);
Assignee:
CREATV MICROTECH, INC., Potomac, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61P 35/00 (2006.01); G01N 33/574 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); C07K 16/2827 (2013.01); C07K 2317/76 (2013.01); G01N 2333/70532 (2013.01);
Abstract
Methods of using detection of PD-L1 expression by circulating cancer cells in the screening, monitoring, treatment and diagnosis of cancer in subjects are disclosed. The methods are based on assaying one or more of circulating tumor cells (CTCs), epithelial to mesenchymal transition CTCs (EMTCTCs), cancer associated macrophage-like cells (CAMLs), and cancer associated vascular endothelial cells (CAVEs) isolated from a subject having cancer for PD-L1 expression.