The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

May. 21, 2018
Applicants:

Fundació Institut DE Recerca Biomèdica (Irb Barcelona), Barcelona, ES;

Institució Catalana DE Recerca I Estudi Avançats, Barcelona, ES;

Inventors:

Roger Gomis, Barcelona, ES;

Evarist Planet, Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); A61K 47/54 (2017.01); G01N 33/574 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 47/548 (2017.08); C07K 16/2875 (2013.01); G01N 33/57423 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/82 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to a method for the diagnosis or the prognosis of metastasis in lung cancer which comprises determining if the c-MAF gene is amplified in a primary tumor sample. Likewise, the invention also relates to a method for the diagnosis or the prognosis of metastasis in lung cancer, as well as to a method for determining the tendency to develop bone metastasis with respect to metastasis in other organs, which comprise determining the c-MAF gene expression level. Finally, the invention relates to the use of a c-MAF inhibitor as therapeutic target for treating the lung cancer.


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