The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Aug. 14, 2019
Applicant:
Nitto Denko Corporation, Osaka, JP;
Inventors:
Kenjirou Minomi, Osaka, JP;
Jihua Liu, San Marcos, CA (US);
Li Wang, San Diego, CA (US);
Bharat Majeti, San Diego, CA (US);
Roger Adami, Carlsbad, CA (US);
Wenbin Ying, San Diego, CA (US);
Assignee:
Nitto Denko Corporation, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 9/127 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12N 15/113 (2013.01); C12N 15/1135 (2013.01); C12Y 205/01018 (2013.01); C12N 2310/14 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/344 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01);
Abstract
This invention provides methods and compositions for preventing, treating or ameliorating one or more symptoms of a malignant tumor, which may be associated with KRAS mutation in a mammal in need thereof, by administering to the mammal a therapeutically effective amount of a composition comprising one or more RNAi molecules that are active in reducing expression of GST-π.