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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11352610 B1

PDFFull Text
Date of Patent:
Jun. 07, 2022

Filed:

Feb. 28, 2019

Diacylglycerol acyltransferase (dga1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous dga1

Applicant:

Ginkgo Bioworks, Inc., Boston, MA (US);

Inventors:

Elena E. Brevnova, Belmont, MA (US);

Arthur J. Shaw, IV, Belmont, MA (US);

Emily H. Greenhagen, Melrose, MA (US);

Assignee:

Ginkgo Bioworks, Inc., Boston, MA (US);

Attorneys:

Foley Hoag LLP

Janine Ladislaw

Mohanad Mossalam

Primary Examiner:

Tekchand Saidha

Int. Cl.
CPC ...
C12N 9/10 (2006.01); C12P 7/6445 (2022.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); C12P 7/6445 (2013.01); C12Y 203/0102 (2013.01);
Abstract

DGA1 catalyzes the final enzymatic step for converting acyl-CoA and 1,2-diacylglycerol to triacylglycerols (TAG) and CoA in yeast. Disclosed are methods for expression in an oleaginous yeast host of polynucleotide sequences encoding DGA1 from, or. Also described herein are engineered recombinant host cells ofcomprising heterologous DGA1 polynucleotides encoding DGA1 proteins, or functionally active portions thereof, having the capability of producing increased lipid production and possessing the characteristic of enhanced glucose consumption efficiency.

Find Patent Forward Citations

Brevnova, Elena. (2022). Diacylglycerol acyltransferase (dga1) polynucleotides, and methods of increasing yeast cell lipid production by overexpression of heterologous dga1 (U.S. Patent No. 11352610). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11352610

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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