The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Sep. 05, 2017
Applicants:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

F. Hoffmann-la Roche Ag, Basel, CH;

Inventors:

Koichiro Yoneyama, Tokyo, JP;

Christophe Schmitt, Basel, CH;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/36 (2006.01); A61P 7/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/36 (2013.01); A61P 7/04 (2018.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/94 (2013.01);
Abstract

An objective of the present invention is to provide an effective pharmaceutical composition or a dosage regimen for preventing and/or treating bleeding, a disease accompanying bleeding, or a disease caused by bleeding. The inventors discovered that by administering a pharmaceutical composition comprising a bispecific antigen-binding molecule that recognizes (a) blood coagulation factor IX and/or activated blood coagulation factor IX and (b) blood coagulation factor X and/or activated blood coagulation factor X according to a given dosage regimen, bleeding, a disease accompanying bleeding, or a disease caused by bleeding can be prevented and/or treated more effectively.


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