The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Dec. 15, 2017
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Jamie M. Orengo, Cortlandt Manor, NY (US);
Namita A. Gandhi, Monroe, NJ (US);
Allen Radin, New York, NY (US);
Ana Kostic, New York, NY (US);
Andrew J. Murphy, Croton-on-Hudson, NY (US);
George D. Yancopoulos, Yorktown Heights, NY (US);
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Abstract
The present invention provides methods for treating an allergy by administering one or more antibodies that bind specifically to the allergen. In certain embodiments, the antibodies useful for treating an allergen, bind specifically to the cat allergen, Fel d1. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to Fel d1. The antibodies of the invention are useful for binding to the Fel d1 allergen in vivo, thus preventing binding of the Fel d1 allergen to pre-formed IgE on the surface of mast cells or basophils. In doing so, the antibodies act to prevent the release of histamine and other inflammatory mediators from mast cells and/or basophils, thus ameliorating the untoward response to the cat allergen in sensitized individuals.