The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Sep. 28, 2018
Applicant:
Vacdiagn Biotechnology Co., Ltd, Suzhou, CN;
Inventors:
Assignee:
Vacdiagn Biotechnology Co., Ltd, Jiangsu, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/00 (2006.01); C07K 14/005 (2006.01); C07K 14/16 (2006.01); C07K 14/02 (2006.01); C07K 14/73 (2006.01); A61P 31/22 (2006.01); A61P 35/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70514 (2013.01); A61K 39/001186 (2018.08); A61K 39/001188 (2018.08); A61K 39/12 (2013.01); A61P 31/22 (2018.01); A61P 35/00 (2018.01); C07K 14/005 (2013.01); A61K 2039/575 (2013.01);
Abstract
Disclosed are a fusion peptide of CD4 helper T cell epitopes, a nucleic acid encoding the same and an immunogenic composition comprising the same. The epitope fusion peptide comprises a cytomegalovirus epitope and an influenza virus epitope. The epitope fusion peptide can substantially improve the level of cellular immune response to a target immunogen, particularly a weak immunogen, and is an effective means for overcoming the immune tolerance of immune system to an antigen, particularly to a tumor antigen or an infection-related antigen, and is suitable for efficiently enhancing the efficacy of vaccine.