The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Jul. 17, 2020
Astrazeneca Ab, Sodertalje, SE;
Bernard Barlaam, Cambridge, GB;
Christopher De Savi, Wilmington, DE (US);
Janet Hawkins, Cambridge, GB;
Alexander Hird, Wilmington, DE (US);
Michelle Lamb, Wilmington, DE (US);
Kurt Pike, Cambridge, GB;
Melissa Vasbinder, Wilmington, DE (US);
ASTRAZENECA AB, Sodertalje, SE;
Abstract
Provided are a series of novel pyridine or pyrimidine derivatives which inhibit CDK9 and may be useful for the treatment of hyperproliferative diseases. In particular the compounds are of use in the treatment of proliferative disease such as cancer including hematological malignancies such as acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia, diffuse large B cell lymphoma, Burkitt's lymphoma, follicular lymphoma and solid tumors such as breast cancer, lung cancer, neuroblastoma and colon cancer.