The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Mar. 18, 2019
Applicant:
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Inventors:
Kenner Cralle Rice, Bethesda, MD (US);
Arthur E. Jacobson, Rockville, MD (US);
Fuying Li, Shanghai, CN;
Eugene S. Gutman, Holland, PA (US);
Eric W. Bow, Washington, DC (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/08 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 491/08 (2013.01); A61P 29/00 (2018.01);
Abstract
The present invention is directed to a compound having Formula (I) and its enantiomer: wherein the definitions of n, R, X, Y and Y, and Z are provided in the disclosure. The invention is also directed to pharmaceutical compositions of the disclosed compounds, as well as their use as opioid-like agonists in the treatment of pain.