The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Jul. 06, 2018
Applicant:

Xuanzhu Biopharmaceutical Co., Ltd., Shijiazhuang, CN;

Inventors:

Wenkui Ken Fang, Shandong, CN;

Bo Chen, Shandong, CN;

Tingzhong Wang, Shandong, CN;

Jing Cheng, Shandong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); A61K 31/428 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/08 (2013.01);
Abstract

The present invention belongs to the technical field of pharmaceuticals, and particularly relates to a compound of formula (I), a pharmaceutically acceptable salt thereof, an ester thereof or a stereoisomer of the compound, the salt or the ester, wherein R, X, X, M, Ar, ring A, ring B and L are as defined in the specification. The present invention also relates to: a preparation method for the compound, a pharmaceutically acceptable salt thereof, an ester thereof or a stereoisomer of the compound, the salt or the ester; a pharmaceutical composition and pharmaceutical formulation containing the compound, the pharmaceutically acceptable salt, the ester or the stereoisomer of the compound, the salt or the ester; and a use of the compound, the pharmaceutically acceptable salt, the ester or the stereoisomer of the compound, the salt or the ester in the preparation of a medicament for treating and/or preventing FXR-mediated diseases.


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