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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11352354 B1

PDFFull Text
Date of Patent:
Jun. 07, 2022

Filed:

Aug. 03, 2018

Substituted penta-fused hexa-heterocyclic compounds, preparation method therefor, drug combination and use thereof

Applicant:

Xiamen University, Xiamen, CN;

Inventors:

Xianming Deng, Xiamen, CN;

Wei Huang, Xiamen, CN;

Xihuan Sun, Xiamen, CN;

Ting Zhang, Xiamen, CN;

Zhixiang He, Xiamen, CN;

Yan Liu, Xiamen, CN;

Xinrui Wu, Xiamen, CN;

Baoding Zhang, Xiamen, CN;

Xiaoyang Li, Xiamen, CN;

Jingfang Zhang, Xiamen, CN;

Yun Chen, Xiamen, CN;

Li Li, Xiamen, CN;

Qingyan Xu, Xiamen, CN;

Zhiyu Hu, Xiamen, CN;

Assignee:

Xiamen University, Xiamen, CN;

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

John M Mauro

Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 473/34 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 35/00 (2018.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

A type of substituted penta-fused hexa-heterocyclic compounds having selective inhibition for PIKfyve kinase, a pharmaceutically acceptable salt and pharmaceutically acceptable solvate thereof, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with PIKfyve in vivo, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.

Find Patent Forward Citations

Deng, Xianming. (2022). Substituted penta-fused hexa-heterocyclic compounds, preparation method therefor, drug combination and use thereof (U.S. Patent No. 11352354). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11352354

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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