The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Aug. 21, 2020
Applicant:

Heptares Therapeutics Limited, Cambridge, GB;

Inventors:

Giles Albert Brown, Cambridge, GB;

Julie Elaine Cansfield, Cambridge, GB;

Miles Stuart Congreve, Cambridge, GB;

Benjamin Gerald Tehan, Cambridge, GB;

Barry John Teobald, Cambridge, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 401/14 (2006.01); C07D 401/08 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 491/107 (2006.01); C07D 498/08 (2006.01); A61P 25/28 (2006.01); A61P 25/02 (2006.01); A61P 25/18 (2006.01); C07D 413/14 (2006.01); C07D 451/02 (2006.01); C07D 451/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 25/02 (2018.01); A61P 25/18 (2018.01); A61P 25/28 (2018.01); C07D 401/08 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 451/02 (2013.01); C07D 451/14 (2013.01); C07D 491/107 (2013.01); C07D 498/08 (2013.01);
Abstract

This invention relates to compounds that are agonists of the muscarinic Mand/or Mreceptor and which are useful in the treatment of diseases mediated by the muscarinic Mand Mreceptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula (1) wherein X; X; Rand Rare as defined herein.


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