The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Jul. 31, 2017
Applicants:

Canon U.s.a., Inc., Melville, NY (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Robert J. Pryor, Midvale, UT (US);

Carl T. Wittwer, Salt Lake City, UT (US);

Scott O. Sundberg, Yorktown, VA (US);

Ivor T. Knight, Erie, PA (US);

Joseph T. Myrick, West Point, VA (US);

Robert A. Palais, Salt Lake City, UT (US);

Jeanette Y. Paek, Los Alamitos, CA (US);

Assignees:

Canon U.S.A., Inc., Melville, NY (US);

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6827 (2018.01); B01L 3/00 (2006.01); C12Q 1/68 (2018.01); B01L 7/00 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01L 3/50851 (2013.01); B01L 7/52 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6827 (2013.01);
Abstract

A method and system have been provided to perform high speed nucleic acid melting analysis while still obtaining accurate melting curve sufficient for genotyping. This rapid ability to interrogate DNA should be useful whenever time to result is important, such as in molecular point of care testing. Specifically, microfluidics enables genotyping by melting analysis at rates up to 50° C./s, requiring less than is to acquire an entire melting curve. High speed melting reduces the time for melting analysis, decreases errors, and improves genotype discrimination of small amplicons.


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