The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Dec. 21, 2017
Applicant:

Duke University, Durham, NC (US);

Inventors:

Warren M. Grill, Chapel Hill, NC (US);

David T. Brocker, Cary, NC (US);

Alexander R. Kent, Durham, NC (US);

Assignee:

DUKE UNIVERSITY, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/36 (2006.01); G16H 20/30 (2018.01); G16H 50/50 (2018.01); G16B 5/20 (2019.01);
U.S. Cl.
CPC ...
A61N 1/36139 (2013.01); A61N 1/3606 (2013.01); A61N 1/36067 (2013.01); A61N 1/36075 (2013.01); A61N 1/36132 (2013.01); A61N 1/36171 (2013.01); G16B 5/20 (2019.02); G16H 20/30 (2018.01); G16H 50/50 (2018.01);
Abstract

The present invention relates to methods that enable one to design temporal patterns for the optimal stimulation of a nervous system, one or more nerve cells, or nervous tissue. In one embodiment, the present invention relates to methods to design improved stimulation patterns and/or genetic algorithms for the optimal stimulation of a nervous system, one or more nerve cells, or nervous tissue. In one embodiment, the present invention utilizes a model-based design to achieve a more optimal stimulation pattern for use in connection with a nervous system, one or more nerve cells, or nervous tissue (e.g., a human nervous system). In another embodiment, the model-based design of the present invention utilizes a systematic search method to identify parameters (e.g., design variables) that minimize a cost function (e.g., optimize the fitness of a particular design). In one instance, the system and method of the present invention is demonstrated via optimal temporal patterns of electrical stimulation for a nervous system, one or more nerve cells, or nervous tissue.


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