The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Jun. 30, 2016
Applicant:
Seagen Inc., Bothell, WA (US);
Inventors:
Timothy Lewis, Kenmore, WA (US);
Lori Westendorf, Snohomish, WA (US);
Django Sussman, Seattle, WA (US);
Che-Leung Law, Shoreline, WA (US);
Assignee:
Seagen Inc., Bothell, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); C07K 16/28 (2006.01); A61K 47/65 (2017.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 47/65 (2017.08); A61K 47/6811 (2017.08); A61K 47/6851 (2017.08); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); A61K 2039/505 (2013.01); A61K 2039/572 (2013.01); A61K 2121/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/567 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/92 (2013.01);
Abstract
Disclosed are antibodies, including antibody drug conjugates, that specifically bind to NTB-A. Also disclosed are methods for using the anti-NTB-A antibodies to detect or modulate activity of (e.g., inhibit proliferation of) an NTB-A-expressing cell, as well as for diagnoses or treatment of diseases or disorders (e.g., cancer) associated with NTB-A-expressing cells, such as multiple myeloma, non-Hodgkin lymphoma and acute myeloid leukemia.