The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2022

Filed:

Oct. 10, 2014
Applicant:

College of Medicine Pochon Cha University Industry-academic Cooperation Foundation, Pocheon-si, KR;

Inventors:

Jisook Moon, Seoul, KR;

Hyun-Seob Lee, Namyangju-si, KR;

Yeon-Ho Shin, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); C12N 5/07 (2010.01); C12N 5/00 (2006.01); C12N 5/073 (2010.01); C12N 5/079 (2010.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/12 (2013.01); C12N 5/0018 (2013.01); C12N 5/0603 (2013.01); C12N 5/0618 (2013.01); A61K 35/00 (2013.01); C12N 5/06 (2013.01); C12N 2500/02 (2013.01); C12N 2500/38 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2533/32 (2013.01); C12N 2533/52 (2013.01);
Abstract

The present invention provides a method for proliferating neural progenitor cells and a composition for treating neurological diseases, the composition including a proliferated neural progenitor cell. When a fetal neural progenitor cell is cultured under a hypoxia condition and/or in a medium containing tocoperol, tocoperol acetate, or a mixture thereof, the improved cell proliferation rates of the fetal neural progenitor cell are confirmed. In addition, considering an effect of the neural progenitor cell on preventing differentiation thereof into neurons at the time of proliferation, the present disclosure may contribute to mass production of neural stem cells, and accordingly, the proliferated neural progenitor cell is expected to be utilized in the treatment of a neurological disease.


Find Patent Forward Citations

Loading…