The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 2022
Filed:
Apr. 12, 2018
Applicant:
Italfarmaco S.p.a., Milan, IT;
Inventors:
Barbara Vergani, Macherio, IT;
Gianluca Caprini, Somma Lombardo, IT;
Gianluca Fossati, Milan, IT;
Maria Lattanzio, Milan, IT;
Mattia Marchini, Milan, IT;
Gianfranco Pavich, Desio, IT;
Marcello Pezzuto, Paderno Dugnano, IT;
Chiara Ripamonti, Monza, IT;
Giovanni Sandrone, Novara, IT;
Christian Steinkühler, Rome, IT;
Andrea Stevenazzi, Milan, IT;
Assignee:
ITALFARMACO SPA, Milan, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4365 (2006.01); A61K 31/427 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01); A61K 31/4196 (2006.01); A61K 31/5377 (2006.01); A61K 31/41 (2006.01); A61K 31/55 (2006.01); A61K 31/497 (2006.01); A61K 31/4245 (2006.01); A61K 31/437 (2006.01); A61K 31/433 (2006.01); A61K 31/4725 (2006.01); A61K 31/4439 (2006.01); A61K 31/4709 (2006.01); A61K 31/501 (2006.01); A61K 31/454 (2006.01); C07D 249/12 (2006.01); C07D 249/08 (2006.01); C07D 401/06 (2006.01); C07D 401/04 (2006.01); C07D 271/06 (2006.01); C07D 271/10 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 417/06 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 257/04 (2006.01); C07D 409/14 (2006.01); C07D 409/04 (2006.01); C07D 403/04 (2006.01); C07D 405/06 (2006.01); C07D 495/04 (2006.01); C07D 413/04 (2006.01); A61P 35/00 (2006.01); A61P 29/00 (2006.01); A61P 27/00 (2006.01); A61P 25/00 (2006.01); C07D 271/113 (2006.01); C07D 285/125 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); A61K 31/41 (2013.01); A61K 31/4196 (2013.01); A61K 31/427 (2013.01); A61K 31/4245 (2013.01); A61K 31/433 (2013.01); A61K 31/437 (2013.01); A61K 31/4365 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 249/08 (2013.01); C07D 249/12 (2013.01); C07D 257/04 (2013.01); C07D 271/06 (2013.01); C07D 271/10 (2013.01); C07D 271/113 (2013.01); C07D 285/125 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 417/04 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C07D 491/107 (2013.01); C07D 495/04 (2013.01);
Abstract
The present invention relates to novel benzohydroxamic compounds of formula (I) and (II) and pharmaceutically acceptable salts, isomers and prodrugs thereof, exhibiting a high selective inhibitory activity against histone deacetylase 6 (HDAC6) enzyme.