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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11351125 B1

PDFFull Text
Date of Patent:
Jun. 07, 2022

Filed:

Feb. 21, 2017

Poly(n-butyl cyanoacrylate) nanoparticle with dual modifications, preparation method and use thereof

Applicant:

Xuanwu Hospital of Capital Medical University, Beijing, CN;

Inventors:

Lan Zhang, Beijing, CN;

Xiao Hu, Beijing, CN;

Lin Li, Beijing, CN;

Assignee:

Xuanwu Hospital of Capital Medical University, Beijing, CN;

Attorney:

Wolf, Greenfield & Sacks, P.C.

Primary Examiner:

Nissa M Westerberg

Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 47/32 (2006.01); A61K 9/51 (2006.01); A61K 49/00 (2006.01); A61P 25/00 (2006.01); A61K 31/337 (2006.01); A61K 47/42 (2017.01); A61K 47/34 (2017.01);
U.S. Cl.
CPC ...
A61K 9/5138 (2013.01); A61K 9/14 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 9/5192 (2013.01); A61K 31/337 (2013.01); A61K 49/0039 (2013.01); A61K 49/0093 (2013.01); A61P 25/00 (2018.01); A61K 47/34 (2013.01); A61K 47/42 (2013.01);
Abstract

The invention relates to a poly(n-butyl cyanoacrylate) nanoparticle with dual modifications, a drug delivery system comprising the nanoparticle, and a method for preparing the nanoparticle or the drug delivery system. The nanoparticle is modified with a first modifier and a second modifier on the surface, the first modifier is a hydrophilic polymer, and the second modifier is an amino acid and/or a lipid. The invention further relates to a use of the nanoparticle in promoting drug penetration across the blood brain barrier in a subject.

Find Patent Forward Citations

Zhang, Lan. (2022). Poly(n-butyl cyanoacrylate) nanoparticle with dual modifications, preparation method and use thereof (U.S. Patent No. 11351125). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11351125

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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