The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

May. 17, 2017
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Kenneth S. Suslick, Champaign, IL (US);

Zheng Li, Urbana, IL (US);

Maria K. LaGasse, Lenexa, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/12 (2006.01); G01N 21/78 (2006.01); G01N 33/487 (2006.01); G01N 31/22 (2006.01); G01N 21/80 (2006.01);
U.S. Cl.
CPC ...
G01N 33/12 (2013.01); G01N 21/78 (2013.01); G01N 33/487 (2013.01); G01N 21/80 (2013.01); G01N 31/22 (2013.01); G01N 31/221 (2013.01); G01N 2201/0221 (2013.01);
Abstract

The present disclosure provides methods for detection and quantification of trimethylamine (TMA) or trimethylamine oxide (TMAO) comprising passing a sample over a sensor comprising a substrate having a plurality of chemically responsive dyes selected from the following classes of chemically responsive dyes: metal-containing dyes, pH indicators, or solvatochromic/vapochromic dyes. The disclosure also provides devices and sensors for the detection and quantification of TMA, and methods of diagnosing a subject having trimethylaminuria (TMAU).


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