The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Dec. 30, 2014
Applicants:

Canon U.s. Life Sciences, Inc., Rockville, MD (US);

University of Maryland, College Park, MD (US);

Inventors:

Ian M. White, Ellicott City, MD (US);

Stephen Restaino, Columbia, MD (US);

Marina Pranda, Rockville, MD (US);

Assignees:

Canon U.S.A., Inc., Melville, NY (US);

University of Maryland, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/24 (2006.01); C12M 3/06 (2006.01); C12Q 1/34 (2006.01); C12M 3/00 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/24 (2013.01); C12M 3/00 (2013.01); C12M 23/16 (2013.01); C12Q 1/34 (2013.01); C12Q 1/37 (2013.01);
Abstract

The present invention relates to methods and systems for cell lysis in a microfluidic device. More specifically, embodiments of the present invention relate to methods and systems for rapid continuous flow pathogen cell lysis. In one embodiment, the microfluidic device comprises a microfluidic channel, a microporous structure within the channel, and an enzyme immobilized on the surface of the microporous structure configured to lyse pathogen cells in fluid flowing through the microfluidic channel.


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