The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Jul. 11, 2018
Applicant:

Tokyo University of Pharmacy and Life Sciences, Hachioji, JP;

Inventors:

Takanori Kanazawa, Hachioji, JP;

Yuuki Takashima, Hachioji, JP;

Hisako Ibaraki, Hachioji, JP;

Shunsuke Shiraishi, Hachioji, JP;

Ei Nakata, Hachioji, JP;

Yusuke Iriyama, Funabashi, JP;

Keiichiro Otsuka, Shiraoka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61K 9/107 (2006.01); A61K 9/14 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 47/34 (2017.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/1075 (2013.01); A61K 9/14 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 47/34 (2013.01); A61K 47/42 (2013.01); C12N 2310/11 (2013.01); C12N 2310/141 (2013.01); C12N 2310/3183 (2013.01);
Abstract

This is to provide a composition for delivering a nucleic acid and a nucleic acid-containing composition which ensure stability of a nucleic acid drug, have a high intracellular introduction rate, can efficiently express the function of a nucleic acid drug, and have low cytotoxicity. Disclosed is a composition for delivering a nucleic acid and a nucleic acid-containing composition each comprises a block copolymer in which a polyethylene glycol segment and a hydrophobic polyester segment are linked, and a peptide having 4 to 30 residues containing at least one selected from the group consisting of arginine and lysine.


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