The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 31, 2022
Filed:
Jul. 31, 2016
Applicant:
Asclepius (Suzhou) Technology Company Group Co., Ltd., Suzhou, CN;
Inventor:
Huashun Li, Suzhou, CN;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C12N 5/0786 (2010.01); A61P 35/00 (2006.01); C12N 15/85 (2006.01); C12N 5/0783 (2010.01); C12N 15/62 (2006.01); A61K 38/17 (2006.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0645 (2013.01); A61K 38/17 (2013.01); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 5/10 (2013.01); C12N 15/62 (2013.01); C12N 15/85 (2013.01); C12N 2740/15041 (2013.01); C12N 2740/16043 (2013.01);
Abstract
Provided is a method for modifying a chimeric antigen receptor-modified T cell (CAR-T cell). The method comprises expressing an SCFV-CDS TM-4-1BB-CD3ζ molecule in a T cell. The CAR-T cell prepared using the method can specifically recognize and bind to a tumor cell with elevated expression of a ROBO1 protein, and can be used to prevent and treat a corresponding tumor-related disease.
Li, Huashun. (2022). Anti-robo1 car-t cell, and preparation and application thereof (U.S. Patent No. 11345893). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11345893
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile