The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 31, 2022

Filed:

Apr. 24, 2020
Applicants:

Agenus Inc., Lexington, MA (US);

Ludwig Institute for Cancer Research Ltd, Zurich, CH;

Memorial Sloan Kettering Cancer Center, New York, NY (US);

Inventors:

Marc Van Dijk, Bosch en Duin, NL;

Cornelia Anne Mundt, Lörrach, DE;

Gerd Ritter, New York, NY (US);

Jedd David Wolchok, New York, NY (US);

Taha Merghoub, Jersey City, NJ (US);

Roberta Zappasodi, New York, NY (US);

Rikke Bæk Holmgaard, New York, NY (US);

David Schaer, Mamaroneck, NY (US);

David Adam Savitsky, Boxford, MA (US);

Nicholas Stuart Wilson, San Carlos, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); C07K 16/2803 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The instant disclosure provides antibodies that specifically bind to human PD-1 and antagonize PD-1 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.


Find Patent Forward Citations

Loading…